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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKD2 All Species: 26.36
Human Site: S591 Identified Species: 72.5
UniProt: Q13563 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13563 NP_000288.1 968 109691 S591 S Q L S T T M S R C A K D L F
Chimpanzee Pan troglodytes XP_001168415 805 91946 Y496 F A Y A Q L G Y L L F G T Q V
Rhesus Macaque Macaca mulatta XP_001099242 969 109684 S592 S Q L S T T M S R C A K D L F
Dog Lupus familis XP_544974 908 103725 S531 S Q L S T T M S R C A K D L F
Cat Felis silvestris
Mouse Mus musculus O35245 966 108978 S589 S Q L S T T M S R C A K D L F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509851 916 103775 S520 S Q L S S T L S R C A K D I I
Chicken Gallus gallus NP_001026311 881 100576 S505 S Q L S T T M S R C V K D V V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1S7 716 80416 N407 D D V T S S E N S Y L N I K A
Sea Urchin Strong. purpuratus NP_999827 907 103454 S528 T Q L S S T L S R C A K D V G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43 98.4 88 N.A. 90.2 N.A. N.A. 40 74.6 N.A. N.A. N.A. N.A. N.A. 29.8 48.6
Protein Similarity: 100 60.3 98.9 90.5 N.A. 93.8 N.A. N.A. 56.4 83.3 N.A. N.A. N.A. N.A. N.A. 46.2 64.9
P-Site Identity: 100 0 100 100 N.A. 100 N.A. N.A. 73.3 80 N.A. N.A. N.A. N.A. N.A. 0 66.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 N.A. N.A. 93.3 86.6 N.A. N.A. N.A. N.A. N.A. 33.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 0 0 0 0 0 67 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0 % C
% Asp: 12 12 0 0 0 0 0 0 0 0 0 0 78 0 0 % D
% Glu: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % E
% Phe: 12 0 0 0 0 0 0 0 0 0 12 0 0 0 45 % F
% Gly: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 78 0 12 0 % K
% Leu: 0 0 78 0 0 12 23 0 12 12 12 0 0 45 0 % L
% Met: 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 78 0 0 12 0 0 0 0 0 0 0 0 12 0 % Q
% Arg: 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 % R
% Ser: 67 0 0 78 34 12 0 78 12 0 0 0 0 0 0 % S
% Thr: 12 0 0 12 56 78 0 0 0 0 0 0 12 0 0 % T
% Val: 0 0 12 0 0 0 0 0 0 0 12 0 0 23 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 12 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _